Casa Guilherme de Almeida, Biographical and literary museum in Perdizes District, São Paulo, Brazil.

Casa Guilherme de Almeida is a house museum in São Paulo that displays the collections of a major Brazilian poet and translator. The residence contains over 15,000 objects including manuscripts, photographs, correspondence, artwork, and an extensive library, all preserved in the original context of the living spaces.

Designed by Silvio Jaguaribe Eckman in 1944 and finished in 1946, the house was bought from widow Baby de Almeida by governor Abreu Sodré after the poet's death in 1969. It opened as a museum on 13 March 1979 under Paulo Egydio Martins and was formally constituted on 1 June 1983 as the Museu da Literatura - Casa Guilherme de Almeida. Closed in September 2006 for structural repairs, it reopened on 11 December 2010.

The house keeps the name Casa da Colina, the poet's own nickname for the hilltop residence. Its rooms hold works given by visiting modernists such as Tarsila do Amaral, Anita Malfatti, Di Cavalcanti and Victor Brecheret. The museum also runs the Centro de Estudos de Tradução Literária, which teaches literary translation.

The museum is open Tuesday through Sunday and offers guided tours by reservation to explore the rooms and collections. Visitors should plan ahead since tours are conducted in small groups and daily visitor numbers may be limited.

The house was designed by architect Silvio Jaguaribe Eckman in 1944 and finished in 1946, the year Guilherme de Almeida and his wife Baby moved in. Friends found his choice of the then sparsely built Sumaré district odd, but the poet prized the isolation, calling the property Casa da Colina and writing that the place was so high and so alone he did not need to raise his eyes to look at the sky.