Kafue National Park, National park in Central Province, Zambia

Kafue National Park covers about 22,400 km² across North Western, Central and Southern provinces, making it Zambia's largest national park. Most of it is miombo woodland of Brachystegia, Julbernardia and Isoberlinia, with teak and mopane forest in the south and centre. The Busanga Plains, seasonally flooded grasslands along the Lufupa river, lie in the far north-west, and the Kafue flows into the Itezhi-Tezhi reservoir partly inside the park.

The park was established in the early 1950s to protect one of Africa's largest wildlife concentrations. Uncontrolled hunting in subsequent decades severely reduced populations of several major species before management efforts improved conditions.

The park is named after the Kafue River, which crosses it and feeds the Itezhi-Tezhi reservoir. The Nkoya people of Mwene Kabulwebulwe were moved from their hunting grounds into Mumbwa District in 1924, and in 2021 Nkoya leaders called for a new Kafue Province, citing little benefit from tourism in the park.

Visitors can reach the park by public transportation and find camping options along the main highway with varying levels of amenities. Hiring a local guide enhances wildlife viewing experiences and ensures safer navigation through different park sections.

The park holds Zambia's largest cheetah population, and since 2005 it has been treated as a lion conservation unit together with South Luangwa National Park, with over 200 lions recorded. The Kafue lechwe, extirpated here in the 1960s by poaching and dam construction, was reintroduced in 2025.