Tlikakila River, Brook in Lake Clark National Park, Alaska, United States.

Tlikakila River is a waterway in Lake Clark National Park that flows from Summit Lake southwest to Lake Clark through a glacially carved valley. The river features clear, cold water fed by glacier melt and moves through a remote landscape with rocky banks and surrounding peaks.

The Lake Clark Pass near the river served as a trade route for Dena'ina peoples until around the early 1900s, connecting communities across the region. This passage reveals how people historically moved through these mountains for commerce and travel.

The Dena'ina Athabascan name Łiq'a Qilanhtnu means "salmon-are-there river", naming the fish directly. The river lies entirely within Lake Clark National Park, and the Dena'ina name is recorded for it in the park's Dena'ina place-name record.

Getting to the river requires flying in by small aircraft to Summit Lake, followed by walking a short distance overland to reach launching areas. Water conditions change with weather and snowmelt, so travelers need to plan carefully and check conditions before heading out.

The river's Dena'ina name, Łiq'a Qilanhtnu, means "salmon-are-there river", and the Tlikakila is one of three Lake Clark National Park streams designated a national wild river in 1980, alongside the Mulchatna and Chilikadrotna. Floaters must portage 2 miles from Summit Lake to reach the runnable water.