La Perla de La Paz, Commercial building in La Paz, Mexico

La Perla de La Paz, also called Casa Ruffo, is a former trading house founded in 1860 in La Paz, Baja California Sur. Of the original building only the facade remains standing after the fire of 12 October 2006; the shop now operates in an adjacent, more recent building. The surviving wall is protected as part of Mexico's historical heritage.

Antonio J. Ruffo Santa Cruz founded the trading house in 1860 and ran it with his sons Agustín, Antonio and Eduardo. It was first called Don Antonio Ruffo, then Ruffo Hermanos, and finally La Perla de La Paz, after a pearl found in the Bay of La Paz in 1883. It was declared a historical monument in 1986 and largely destroyed by fire on 12 October 2006.

The name comes from a pearl found in the Bay of La Paz in 1883 by Antonio Cervera and Juan Vacaseque C., which according to the account ended up in the crown of the Queen of England. A widely told legend instead has a fisherman find a lemon-sized pearl and display it in the shop, where an English consul tried to buy it before the fisherman gave it to the English sovereign. The building was declared a historical monument in 1986.

Only the facade remains standing after the fire of 12 October 2006, and the site of the former building is now used as a parking lot. The store itself operates from an adjacent, more recent building. The surviving wall is protected as historical heritage, so it cannot be demolished.

The name comes from a pearl the size of a lemon that, according to legend, a fisherman found in the bay and displayed in the shop. An English consul wanted to buy it, but the fisherman gave it to the English sovereign instead. The building was declared a monument in 1986, and after the 2006 fire only one wall was left standing; the site is now used as a parking lot.