Lobo, Ghost town in Culberson County, US.

Lobo is a ghost town in Culberson County, Texas, between the Van Horn and Wylie mountains along U.S. Highway 90. Bill Christ bought the entire community in 1969 and opened a gas station and general store; the store burned in 1976. Three residents of Frankfurt, Germany, purchased Lobo on November 5, 2001, and the German owners were offering the town for sale for $100,000 in 2023.

Van Horn Wells, a bolson aquifer discovered in the mid-19th century, was the only known water source within 100 miles and made the spot a stop on the San Antonio-El Paso Road, served by the San Antonio-San Diego Mail Line and Butterfield Overland Mail from 1857. In 1882 the Southern Pacific Railroad established a watering stop and depot here. A post office opened in 1907 under the name Lobo, and a town site was laid out two years later.

The name comes from the Mexican wolves that once roamed this area. The settlement grew around a railway depot and livestock loading facilities that served regional ranching operations.

The location lies about 12 miles south of Van Horn and is accessible via Highway 90. Visitors should note that much of the site remains private property and access may be restricted or require permission.

Two earthquakes struck in 1929 and 1931, causing significant damage to local buildings. A drop in the water table during the 1960s ended cotton farming operations and led to the settlement's decline.