St. James the Apostle Cathedral, Santiago de Veraguas, Roman Catholic cathedral in Santiago de Veraguas, Panama.

St. James the Apostle Cathedral is the seat of the Diocese of Santiago de Veraguas, located near the central plaza of the city in the Veraguas province of Panama. The building has a central nave and two flanking towers that give the facade its recognizable shape from the street.

The Diocese of Santiago de Veraguas was created in 1963 by the bull "Panamensis Ecclesiae" of Pope Paul VI, and the church became its mother church and cathedral. In 2014 the building was declared a historical monument. In June 2015 a Mass was held there for the repose of former president Juan Demóstenes Arosemena, who governed Panama from 1936 to 1939; his remains were later moved from the cathedral to a mausoleum at the Normal School Juan Demóstenes Arosemena.

The cathedral is dedicated to Saint James the Apostle, patron saint of the city of Santiago de Veraguas. During his festivities the church organizes processions and celebrations in his honour. In June 2015 a Mass was held here for the repose of former president Juan Demóstenes Arosemena, who governed Panama from 1936 to 1939.

The cathedral sits in the center of Santiago, close to the main plaza, and is easy to reach on foot from most parts of the downtown area. It is generally open outside of services, but visitors are expected to dress modestly and keep noise to a minimum inside.

In June 2015 a Mass was held here for the repose of President Juan Demóstenes Arosemena, who governed Panama from 1936 to 1939; his remains were later moved from the cathedral to a mausoleum at the Juan Demóstenes Arosemena Normal School. The building was declared a historical monument in 2014.