Port of South Louisiana, Maritime transportation hub on Mississippi River, Louisiana, United States.

The Port of South Louisiana stretches along the Mississippi River between New Orleans and Baton Rouge with multiple cargo terminals spread across the region. These facilities handle grain shipments, containers, and liquid cargo in separate specialized areas.

The Port of South Louisiana is a continuous chain of terminals along the Mississippi between New Orleans and Baton Rouge, through St. James, St. John the Baptist and St. Charles parishes, with headquarters at LaPlace. It is the largest port complex in the United States and the Americas. In 2012 it received 4,152 vessels and 59,372 river barges, handling 278.9 million tonnes of cargo.

The port's name is used in both English and French, reflecting the bilingual tradition of southern Louisiana. Its terminals run through St. James, St. John the Baptist and St. Charles parishes, where grain barges from the Midwest are unloaded for storage and export. In 2012 the port recorded 4,152 ships and 59,372 river barges.

The port is a working complex of terminals, not a visitor site, so there is no single entrance or viewing platform. Its 54 miles of riverbank run through St. James, St. John the Baptist and St. Charles parishes, with headquarters at LaPlace. The Mississippi channel between New Orleans and Baton Rouge is maintained at a 48-foot draft, so deep-draft ships and barge tows pass close to the levees.

The facility moves American grain from inland farms to ocean-going ships, serving as a crucial link in getting crops to international buyers. Without this transfer point, much of the harvest from the farming heartland would have no easy path to overseas markets.