Twin Pine Casino, Casino establishment in Middletown, California.

Twin Pine Casino is an Indian casino in Middletown, California, owned by the Middletown Rancheria of Pomo Indians. Its 10,000 square feet (930 m2) hold over 500 gaming machines and 12 gaming tables, and a 60-room hotel opened in 2009.

The facility opened in 1994 as a project of the Middletown Rancheria of Pomo Indians to create economic opportunities for the tribe. Expansion came later with the addition of hotel rooms for overnight guests.

The casino is owned and run by the Middletown Rancheria of Pomo Indians, the tribal government whose reservation lies at Middletown. Gaming revenue funds the tribe's own administration and services rather than an outside operator. The property is the rancheria's principal enterprise, opened in November 1994.

The casino floor covers 10,000 square feet (930 m2) and holds over 500 gaming machines and 12 gaming tables. The 60-room hotel opened in 2009, so overnight stays are possible on site. Middletown sits in Lake County, north of Napa County, so allow for a drive rather than a short walk to reach wine country.

The casino floor covers 10,000 square feet and holds more than 500 gaming machines alongside 12 gaming tables. The adjoining hotel was first planned in 2007 and opened in 2009 with 60 rooms, so guests can stay on site rather than drive back after playing.