Church of Sant'Afra, Religious building in Brescia, Italy.

The Church of Sant'Afra is a religious building in Brescia featuring a single nave plan with three chapels on each side. Corinthian columns support the vaulted ceiling throughout the interior, creating the defining architectural structure of the space.

Construction started in 1462 when Benedictine monks from Sant'Eufemia della Fonte monastery received permission to build a new religious structure. This founding marked the establishment of an important place of worship in the city that continued to develop over centuries.

The interior displays paintings by regional artists, including works by Sante Cattaneo and a canvas by Paolo Veronese showing the Martyrdom of Sant'Afra. These artworks reflect the place's importance to local painters across different periods.

The church stands at the east end of Corso Magenta, on the south-east corner of Piazzale Arnaldo. The left entrance opens onto a small chapel of the Crucifixion that does not connect to the nave, while the right entrance leads along a corridor to the crypt and then the sacristy. The building is still open and officiated.

The 15th-century crypt still holds a Madonna by Vincenzo Civerchio, paintings from Sant'Angela Merici by Francesco Giugno showing Saints Faustino and Jovita and Sant'Afra, and fragments of 15th-century frescoes. The casket of Saint Paterius, once kept here, is now in the Museo di Santa Giulia.