Palazzo Balbi Giacomo e Pantaleo, Renaissance palace in Via Balbi, Genoa, Italy

Palazzo Balbi Giacomo e Pantaleo is a Baroque palace in Genoa, built by Bartolomeo Bianco in the 1620s for the Balbi brothers. It has two superimposed apartments sharing a monumental staircase and a U-shaped plan after 1645–1665 changes by Pietro Antonio Corradi. A garden with a stucco nymphaeum by Gian Battista Barberini lies downhill.

Bartolomeo Bianco designed the palazzo in the 1620s for the brothers Giacomo and Pantaleo Balbi, whose wealth came from finance. Francesco Maria Balbi, Giacomo's son, unified the property and had it renovated between 1645 and 1665 by Pietro Antonio Corradi, who added the U-shaped plan and the garden nymphaeum. The building is now home to the humanities departments of the University of Genoa.

The interior holds Baroque frescoes by Valerio Castello depicting mythological scenes such as the abduction of Proserpine. Local artists like Domenico Piola also contributed works that remain visible throughout the rooms.

The building now serves as part of the University of Genoa, so access to its spaces depends on academic schedules and class times. Visitors should check ahead and plan their visits during official university hours.

The 1645 work by Pietro Antonio Corradi, a pupil of Bianco, added rooms on the upper floors, giving the plan the U-shape it keeps today. The garden below was created the same year by demolishing medieval houses; its nymphaeum by Gian Battista Barberini uses rocks, shells and stucco, with Neptune on sea horses above the cascade.