Sacred Prophetic Chamber, Religious burial chamber in Prophet's Mosque, Medina, Saudi Arabia

The Sacred Prophetic Chamber is Aisha bint Abi Bakr's former room, now enclosed within the Prophet's Mosque east of the Rawdah. Its outer brass screen measures 16 m on the north and south sides and 15 m on the east and west, rising about 8 m; the five-sided inner enclosure stands roughly 7 m above the mosque floor. The polished metal panels carry raised gold Arabic calligraphy in horizontal bands, a pointed arch outline and a roundel with the word "الله", with a protruding gold boss near the bottom centre.

Muhammad was buried in 632 in the room of Aisha, his wife, where he died; Abu Bakr was buried beside him in 13 AH and Umar ibn al-Khattab in 24 AH. Under al-Walid I (715–717), at the suggestion of Umar ibn Abd al-Aziz, the chamber was incorporated into the enlarged Prophet's Mosque and enclosed by a high wall. In 557 AH Nur al-Din Zengi sank a lead-filled trench around it, and in 668 AH Baybars added a wooden screen.

Visitors stand before a green dome and offer greetings to the Prophet, treating the area with respect and silence. People from all over the world see this moment as an important part of their religious journey and move slowly along the outer walls.

Men and women use separate entrances and must follow religious dress codes covering arms, legs, and head. The area can become very crowded during prayer times, so visiting outside peak hours is advisable.

The fourth grave space inside the chamber has never been used. Aisha offered it for Abd al-Rahman ibn Awf, and later permitted al-Hasan ibn Ali to be buried there, but the Umayyads prevented it. Sunni tradition holds that Jesus, after his descent, will be buried in this spot.