St. John Nepomuk Parish Historic District, Historic district in Soulard neighborhood, St. Louis, United States.

St. John Nepomuk Parish Historic District is a historic district in Soulard, St. Louis, centered on the Gothic Revival church designed by Chicago architect Adolphus Druiding and six ancillary buildings. The church, largely an 1897 reconstruction after a tornado, is built of brick that matches the surrounding Soulard streetscape. The parish school stands across Eleventh Street from the church.

St. John Nepomuk was founded in 1854 as the first national Bohemian parish in the United States. New church buildings went up in 1873 and 1887, but a tornado in 1896 left the church largely damaged; the present structure is mostly an 1897 reconstruction. The parish closed in 2005, and the church has since remained active as a chapel.

St. John Nepomuk was founded in 1854 as the first national Bohemian parish in the United States, and a Czech-language newspaper was once published in one of the parish buildings. The parish closed in 2005, but the church has stayed active as a chapel. The school across Eleventh Street opened in 1869 and was staffed by the School Sisters of Notre Dame.

The site is easy to reach on foot and the exteriors of the buildings can be viewed from the street. The church was designated a City Landmark in 1971, which means the historic features are protected and the facade remains well-maintained.

The parish was founded in 1854 as the first national Bohemian parish in the United States, and a Czech-language newspaper was once published in one of its buildings. The parish closed in 2005, but the church has stayed active as a chapel.