Scarlet Pearl Casino, Gaming resort in D'Iberville, United States.

Scarlet Pearl Casino Resort is a casino and hotel in D'Iberville, Mississippi, with 300 hotel rooms and 68,000 square feet of gaming space, including a high-limit area opened in late 2020. Amenities include a 36-hole miniature golf course, a buffet, three other restaurants, a swimming pool and a fitness center.

First planned as the Can Can Casino Resort and Spa, the project won site approval from the Mississippi Gaming Commission in February 2010, then stalled during the Great Recession. Revised plans under the Scarlet Pearl name were approved in December 2013, groundbreaking followed in July 2014, and the property opened on December 9, 2015, at a cost of $290 million.

The name recalls the original Can Can Casino Resort and Spa, approved by the Mississippi Gaming Commission in February 2010 before the Great Recession stalled the project. Revised plans under the Scarlet Pearl name were approved in December 2013, and the resort opened on December 9, 2015, costing $290 million.

The resort sits in D'Iberville, Mississippi, on the Gulf Coast near Biloxi, and is reached by car. On-site amenities include a swimming pool, a fitness center and a 36-hole miniature golf course, so non-gaming members of a group have things to do while others play.

On October 1, 2019, the Scarlet Pearl sportsbook accepted a $3.5 million wager from Jim "Mattress Mack" McIngvale on the Houston Astros to win the World Series. Over that October he placed $6.2 million in bets at the property, all on the Astros.