Andino Norpatagonica Biosphere Reserve, Biosphere reserve in northern Patagonia, Argentina.

The Andino Norpatagonica Biosphere Reserve is a protected area in northern Patagonia that combines varied landscapes from different elevations. It contains mountain forests, deep lakes, and multiple ecological zones within its boundaries.

The area received UNESCO biosphere reserve status in 2007 to protect its natural resources. This designation encouraged scientific research and sustainable practices throughout the Andean-Patagonian landscape.

The reserve's name links the Andes to northern Patagonia, and its inhabited core is a chain of towns and hamlets: Esquel, Trevelin, Cholila, Lago Puelo, El Hoyo, Epuyén, El Maitén and Leleque in Chubut; Bariloche, El Bolsón and Villa Mascardi in Río Negro; San Martín de los Andes, Junín de los Andes, Aluminé, Villa Traful and Villa La Angostura in Neuquén. Their municipal land lies inside the reserve, so residents farm, keep livestock and run tourism alongside conservation.

The reserve has many hiking trails and observation points scattered throughout, with guided tours led by local naturalist organizations. Plan your visit during warmer months when trails are easier to navigate and weather conditions are more favorable.

The reserve's 2,266,942 hectares span three provinces: Chubut, Río Negro and Neuquén. It adjoins Chile's Southern Andes Temperate Rainforests reserve, together forming a binational unit of 2,168,956 hectares. Within it lie five national parks, including Los Alerces and Nahuel Huapi, plus ten provincial protected areas.