Iglesia de El Sagrario, Renaissance Catholic church in Historic Center, Ecuador.

Iglesia de El Sagrario is a church beside the Metropolitan Cathedral on García Moreno Street, built on an arcade over the filled Zanguña ravine. Its two-body facade alternates Ionic columns below and Corinthian above, with twelve tall columns and four stone sculptures. Inside, the central nave ends in a barrel vault, the side naves are closed by small domes, and a dome with lantern rises over the transept.

Construction began in 1617 under the Confraternity of the Sagrado Sacramento and took nearly a century to reach completion in 1715 through multiple building phases. During this extended period, artistic elements were added progressively, shaping the final appearance of the church.

El Sagrario follows the Sevillian model of a sacramental chapel that is also an independent parish, a form brought from the Cathedral of Seville to Spanish cathedrals in the New World. The church is dedicated to the Holy Sacrament and was funded by the Cofradía del Sagrado Sacramento, which began the foundations in 1617.

The church sits along a main street in the Historic Center and is easily reached on foot, especially when combining a visit with nearby religious buildings like La Compañía de Jesús. Visitors should note that interior lighting varies, and details in higher areas can be easy to miss without looking upward.

The church stands on an arcade that closed the Zanguña ravine, which ran from the El Tejar monastery area to what is now La Marín. Jesuit priest Marcos Guerra, of Neapolitan origin, directed the foundations, sunk fourteen metres on the south side and three on the north to follow the ravine's slope.