Tetlin National Wildlife Refuge, Wildlife refuge along Alaska Highway, United States.

Tetlin National Wildlife Refuge is a large protected area along the Alaska Highway encompassing forests, wetlands, tundra, and lakes throughout the landscape. Glacial rivers run through the terrain, with mountain peaks forming natural boundaries.

Tetlin National Wildlife Refuge was established in 1980 under the Alaska National Interest Lands Conservation Act, protecting the upper Tanana River valley on the U.S. border with Canada. The valley, known as the Tetlin Passage, funnels migratory birds and large mammals between Canada and Alaska. Area residents, including Alaska Native communities, rely on caribou, moose and whitefish as subsistence resources.

Two of the six known humpback whitefish spawning areas in the Yukon River drainage lie inside the refuge, and these fish, along with caribou and moose, are subsistence resources for area residents. Three caribou herds range across the refuge, and local families depend on them for food.

The refuge offers seven viewpoints along the highway and overnight accommodations including a campground at Deadman Lake and remote cabins. Visitors should prepare for changing weather and bring sturdy footwear for exploration.

Two of the six known humpback whitefish spawning areas in the Yukon River drainage lie inside the refuge. Together with caribou and moose, these fish are subsistence resources for area residents, and Arctic grayling, northern pike and burbot also live in its streams and lakes.