Tizatlán, Archaeological site in Tlaxcala, Mexico.

Tizatlán is an archaeological site in Tlaxcala with preserved stone structures and ceremonial platforms from before Spanish arrival. The remains show how ancient builders in central Mexico constructed their buildings and organized their spaces.

This site served as a power center within the Tlaxcallan confederation under Xicotencatl I's leadership before Spanish conquest. It held importance in the region's political structures during pre-Columbian times.

Tizatlán means "Place of chalk" in Nahuatl, a name given by the Teochichimeca who founded the settlement in the 13th century. The site was the fourth tlatocayotl (lordship) of the Tlaxcalteca. In the chapel built over the pre-Hispanic structures, the four lords of the Republic of Tlaxcala were baptized and converted to Christianity.

Tizatlán lies about 8 km from Tlaxcala city, 50 km from Puebla and 123 km from Mexico City, in the town of the same name. The site is under INAH jurisdiction as monument ZA154. A site museum displays artifacts and the history of the excavations.

The site was uncovered in 1927 after the farmer Pánfilo Sánchez reported that the spirit of Huehue Xicohténcatl led him at night to the spot and told him to dig for a treasure. The community dug and found the polychrome altars instead.