Our Lady of the Incarnation Cathedral, San Miguel de Tucumán, National historical cathedral in San Miguel de Tucumán, Argentina.

Our Lady of the Incarnation Cathedral stands on Calle 24 de Septiembre facing Plaza Independencia. Its cream-stone facade has two square towers with reddish bulbous domes, clock faces and arched windows, flanking a portico of six Doric columns, four paired, under a triangular pediment carved in marble by Juan Bautista Finochiaro with the Exodus scene. A blue-and-white tiled dome rises on a drum with eight windows. The interior is a Latin-cross basilica with a wide gabled nave.

The cathedral's site dates from 1685, when Governor Fernando de Mendoza y Mate de Luna moved San Miguel de Tucumán from Ibatín; for long it was a humble adobe church with a gabled roof of muslera tiles. In the mid-19th century, under provincial governor Celedonio Gutiérrez, the Franco-Basque architect Pierre Etcheverry (Pedro Etcheverry in Argentina) designed and directed the new eclectic temple, consecrated on 19 February 1856 with the blessing of vicar Fray Mamerto Esquiú.

Inside, two small old statues of Saints Jude Thaddeus and Simon recall the city's patrons, venerated after a 1578 victory over the Calchaquíes. A wooden Crucifix at the left of the vestibule receives constant veneration from passers-by, and a quebracho cross in one transept arm is traditionally dated to the city's founding at Ibatín and credited with miraculous character.

The building sits in the center of San Miguel de Tucumán and is easily accessible on foot from nearby streets. It welcomes both visitors and worshippers, though it is best to be respectful of scheduled religious ceremonies when planning your visit.

The bronze bells in the two towers predate the present building: they were cast in Chuquisaca during Spanish rule in Upper Peru. In a transept arm stands a quebracho wood cross held to date from the city's founding at Ibatín, to which miraculous properties are attributed.