Cristalino State Park, State park in Mato Grosso, Brazil

Cristalino State Park is a protected area in northern Mato Grosso that spans between the Teles Pires River and Para state boundaries. The landscape includes seasonal forests that give way to tropical rainforest regions across its vast territory.

Cristalino State Park was created on 9 June 2000 with an initial area of 66,900 hectares, to preserve animals and native tree species threatened with extinction. The contiguous Cristalino II State Park was created by decree 2,628 of 30 May 2001; together the two parks cover 184,900 hectares. A consultative council was installed in 2007, and in 2016 the park was supported by the Amazon Region Protected Areas Program.

The park lies in the transition zone between Amazon rainforest and cerrado, where 515 bird species have been recorded, 55 of them endemic, along with 43 reptiles, 29 amphibians, 36 mammals and 16 fish species of commercial or sport value. Ecotourism focused on wildlife observation and hiking generates income for the surrounding area.

Access is by water up the Teles Pires to the Cristalino River mouth, or by the unpaved Quarta Leste road from Alta Floresta with a ferry crossing of the Teles Pires. The dry season runs from May to September, when monthly rainfall stays below 100 mm. SEMA's research station has four bedrooms, one bathroom and a generator.

Serra Rochedo within the park contains numerous water springs that feed clear streams throughout the landscape. These natural springs create visible waterways that visitors can spot while moving through the forest regions.