La Frailesca, Agricultural region in Chiapas, Mexico

La Frailesca is an agricultural region in Chiapas, Mexico, situated between the Sierra Madre mountains and the Central Depression with varying elevations across its landscape. Seven municipalities make up the area, with Villaflores serving as the main administrative center.

The region took its name from Dominican friars who established haciendas and conducted missions during colonial times, shaping early settlement patterns. This religious influence remained a defining part of the territory's development.

The name comes from the many Dominican friars who crossed the region, most of them owners of haciendas who also handled evangelisation. Today most inhabitants are Catholic (69.98%), followed by Protestant churches (8.02%) and non-evangelical biblical churches (8.55%), while 12.77% profess no religion. Locals speak fraylescano, a rural Spanish dialect.

Villaflores, the regional capital, sits on the Central Depression side of the region, while municipalities such as Ángel Albino Corzo and Montecristo de Guerrero climb toward the Sierra Madre, from 279 up to 2,755 m above sea level. Roads link the seven municipalities, but the warm, humid climate brings summer rains, so travel conditions change with elevation and season.

The Belisario Domínguez hydroelectric dam, built in the 1960s, formed the La Angostura reservoir, flooding towns and very fertile farmland and changing both the landscape and the climate of the region. The reservoir lies within La Frailesca's territory between the Sierra Madre and the Central Depression.