Marshlands Plantation House, Federal plantation house in Charleston County, United States.

Marshlands Plantation House is a 2+1⁄2-story Federal-style plantation house in Charleston, South Carolina. It was built in 1810 and listed on the National Register of Historic Places on March 30, 1973. The house was moved in the 1960s from the site of the United States Navy Shipyard to James Island.

Marshlands Plantation House was built in 1810 and added to the National Register of Historic Places on March 30, 1973. In the 1960s the Navy, which needed the original site for its shipyard, set aside $15,000 to move the empty house or demolish it. The City of Charleston took temporary possession and transferred it to the College of Charleston, which relocated it to James Island.

The house's name comes from the marshland setting of its original site on the Cooper River, before the Navy yard took that ground. Its 1810 Federal character survives in the two-and-a-half-story form, and the building now stands on James Island as a College of Charleston property rather than a working plantation.

The house stands on James Island, where the College of Charleston moved it for preservation; it is not open as a regular museum, so there are no posted tour times or visitor facilities. Anyone wishing to see it should first establish current access arrangements with the College of Charleston rather than simply arriving at the site.

The Navy set aside $15,000 to move the empty house, warning it would be demolished otherwise. The City of Charleston took temporary possession and passed it to the College of Charleston, which moved it to James Island.