Reserva de la biosfera Yabotí, Natural reserve in Misiones, Argentina.

The Yabotí Biosphere Reserve is a large protected area in Misiones Province that preserves subtropical forest landscapes with diverse wildlife. The region spans multiple zones and provides habitat for many animal and plant species native to this humid subtropical region.

The reserve was created on 26 August 1993 by Misiones provincial law No. 3041, which incorporated 119 parcels ranging from 1 hectare to 26,285 hectares. It was designated a UNESCO Biosphere Reserve in 1995 under the MAB programme. Its core area is Esmeralda Provincial Park, alongside Moconá Provincial Park, the Guaraní Forest Reserve, Caá Yarí Provincial Park and the Papel Misionero Cultural Nature Reserve.

The Huella Guaraní circuit, designed by the Subsecretaría de Ecoturismo, links visitors with Mbya Guaraní communities living in the reserve; since autumn 2016 these communities have offered lodging and basic services to travellers. The reserve also contains the Guaraní Forest Reserve and the Papel Misionero Cultural Nature Reserve.

The best time to visit is between April and November when water levels allow viewing of the waterfalls. Access is through the town of El Soberbio, from where trails and guided tours lead into the different protected areas.

The reserve's core is Esmeralda Provincial Park, while Moconá Provincial Park and the Guaraní Forest Reserve are among the other protected areas it contains. The reserve was created on 26 August 1993 by Misiones provincial law 3041, which incorporated 119 parcels ranging from 1 hectare to 26,285 hectares.