Antioch Bridge, Road bridge in Sacramento County, United States.

Antioch Bridge is a toll road bridge spanning the San Joaquin River to connect Contra Costa County with Sacramento County. The structure has one traffic lane in each direction and uses steel plate girder construction.

The original bridge from 1926 suffered repeated collisions with ships due to narrow shipping channels. A new structure was built in 1978 to better accommodate river traffic.

The bridge's official name honours State Senator John A. Nejedly of Contra Costa County, who authored Senate Bill 25, enacted as Chapter 765 of the California Statutes of 1972, authorising revenue bonds for a replacement span. The naming was decided shortly before the new bridge opened in December 1978. Drivers see the name on signs along State Route 160.

Vehicles pay a toll using electronic collection systems when crossing the bridge. The single lane in each direction means traffic moves carefully, especially during busy periods.

The 1970 collision with the freighter Washington Bear left the lift span stuck in the raised position. The bridge tender could not leave and stayed in the control house for 20 hours until local firemen reached him; the bridge then closed for five months of repairs.