Nansha Bridge, Suspension bridge spanning the Pearl River in Guangdong Province, China.

The Nansha Bridge is a 12.891-kilometre all-bridge expressway crossing the Pearl River's Shiziyang channel between Dongguan's Shatian Town and Guangzhou's Nansha District. It comprises two suspension bridges: the Dasha Waterway Bridge with a 1,200-metre main span and the Nizhou Waterway Bridge with a 1,688-metre main span. The Dasha bridge's steel box girder is 49.7 metres wide, the widest integral suspension-bridge girder in the world.

Planning began in 2003 with a pre-feasibility study for the Dongguan Houjie–Panyu Dongchong expressway, and the project was approved by the National Development and Reform Commission in June 2013. Construction started on 28 December 2013 under the name Humen Second Bridge. The main spans closed in 2018, and the bridge opened on 2 April 2019, when it was formally renamed Nansha Bridge.

The bridge carries the Guangzhou-Longchuan Expressway and serves as a critical infrastructure component in the Guangdong-Hong Kong-Macao Greater Bay Area development strategy, supporting regional economic integration and urban expansion across the Pearl River Delta.

The bridge connects Nansha District in Guangzhou with Shatian Town in Dongguan, allowing vehicles to travel at speeds up to 100 kilometers per hour, and on its opening day approximately 50,000 vehicles used the crossing, representing about 18 percent of total daily Pearl River estuary traffic.

The Nizhou Waterway Bridge's main span of 1,688 metres makes it the world's longest steel box girder suspension bridge and China's longest bridge span. Its main cables use 1,960-megapascal steel wire developed in China, and the deck's 49.7-metre-wide steel box girders are the widest of their kind on any suspension bridge.