Pappenheimer Mansion, Demolished mansion site in Midtown Atlanta, United States

The Pappenheimer Mansion stood at 144 Ponce de Leon Avenue NE in Midtown Atlanta, on the north side between Piedmont and Juniper streets. Furniture magnate Oscar Pappenheimer rebuilt it almost immediately after a 1914 fire, adding a music room with a pipe organ and two grand pianos. The house was demolished in 1999; the Marq on Ponce apartment complex now occupies the site.

Furniture magnate Oscar Pappenheimer built his first house on the site around 1900; it burned down in 1914 and he rebuilt almost immediately. The family lived there until the 1930s, when it became a fraternity house for Georgia Tech students. By 1941 it was the Ponce de Leon Infirmary, an ear, nose and throat hospital founded by Dr. Murdock Equen. In 1977 it became Midtown Hospital, closed by the State of Georgia in 1988 and demolished in 1999.

Oscar Pappenheimer's music room held a pipe organ and two grand pianos, and for more than three decades informal concerts were given there. Interest in classical music had waned in Atlanta in the 1890s–1910s, and Pappenheimer was credited as one of the few forces encouraging chamber music performance in the city.

The property's location on Ponce de Leon Avenue placed it in the heart of Midtown Atlanta, making it accessible by local transportation. Visitors should note that the building no longer stands today, having been demolished in 1999 to make room for residential apartments.

The building served its final years as Midtown Hospital before being demolished in 1999. This unexpected medical use was quite different from its origins as an elegant residential property for a wealthy family.