One Enterprise Center, High-rise building in downtown Jacksonville, US.

One Enterprise Center is a 21-story tower in downtown Jacksonville with a distinctive truncated pyramid crown and reflective glass panels that create horizontal stripe patterns across its facade. The 299-foot (91 meter) structure combines glass and concrete to form a recognizable part of the city skyline.

One Enterprise Center was designed by Clark Tribble Harris & Li Architects and completed in 1986 as a 21-floor, 299-foot (91 m) tower in Jacksonville's Northbank. Its current tenants include Rayonier and CBRE Group, and it shares a lobby with the adjacent Omni Hotel.

The structure represents postmodernist architecture of the 1980s, incorporating design elements that moved away from traditional international style.

One Enterprise Center stands in the Northbank area of Downtown Jacksonville, and its lobby is shared with the adjacent Omni Hotel, so the two buildings connect indoors. Tenants in the 21-floor tower include Rayonier and CBRE Group. The coordinates place it on the downtown grid near the St. Johns River.

The building shares its lobby with the adjacent Omni Hotel, so the two structures connect at ground level. Tenants have included the timber company Rayonier and the real estate services firm CBRE Group.