Sierra de Quila, Protected natural area in Jalisco, Mexico.

Sierra de Quila is a protected natural area spanning roughly 15,000 hectares across several municipalities in Jalisco. The landscape features two distinct forest types: pine-oak forests at higher elevations and tropical dry forests at lower levels, with natural springs and waterfalls dispersed throughout.

The area faced deforestation threats until local residents formed a conservation group in the 1950s to protect the forests and water sources. This grassroots effort eventually led to the area's official designation as a protected reserve in 1982.

The name Quila refers to the local Quila plant, and the nearby community of Quila el Grande carries it. Conservation began with the people of Tecolotlán: in the 1950s, led by Gabriel Agraz García de Alba, they organized against forest exploitation, and between 1970 and 1980 the Pro-Conservation Committee of the Forests and Springs of the Sierra de Quila pushed the municipality to protect the area's woods and springs.

The main access is on the west side of Tecolotlán, with other entrances across the municipalities the sierra covers; camping and lodging are available in Tecolotlán and Tenamaxtlán. Rain falls mostly from June to September, with 700–1000 mm a year, so plan around the wet months. The Cerro del Huehuentón viewpoint reaches 2,540 m above sea level.

Sierra de Quila holds 28 mammal species, 90 birds, 15 reptiles and 5 amphibians, about 17% of Jalisco's vertebrates. Its largest mammals are white-tailed deer, collared peccary and puma; no jaguar is recorded in the sources. The CONABIO inventory lists over 715 plant and animal species, 29 of them under NOM-059 risk categories.