Osa Wildlife Sanctuary, Wildlife sanctuary in Piedras Blancas, Costa Rica.

Osa Wildlife Sanctuary (Fundación Santuario Silvestre de Osa), also called Caña Blanca Wildlife Sanctuary, was an animal rescue center on the Osa Peninsula in southwestern Costa Rica, reachable only by boat and entirely surrounded by Piedras Blancas National Park. It began as Carol Patrick's eco-lodge, and by 2003 the property held animal enclosures plus staff housing and dining. The sanctuary is permanently closed to the public.

The facility opened in 2003 when Carol Patrick converted an eco-lodge into a rehabilitation center. This marked the beginning of organized rescue and care for injured animals across the Osa region.

The sanctuary grew out of an eco-lodge run by Carol Patrick, who was asked by local people to take in injured and abandoned animals; the animals in her care kept increasing until she opened the sanctuary in 2003. The centre was permanently closed to the public after government agencies confiscated its caged animals on 19 December 2022.

The sanctuary is permanently closed to the public, so it cannot be visited. It was reachable only by boat, entirely surrounded by Piedras Blancas National Park. On 19 December 2022 government wildlife agencies confiscated the caged animals and trapped some free-roaming ones.

The sanctuary began as Carol Patrick's eco-lodge, and guests' quarters were later converted into animal enclosures, staff housing and a dining building. On 19 December 2022, government wildlife agencies confiscated all caged animals and trapped some free-roaming ones; the site is permanently closed to the public.