Hell Hole Swamp, Protected wilderness area in Berkeley County, United States.

Hell Hole Swamp is a 2,125-acre (9 km2) swamp in northeastern Berkeley County, South Carolina, entirely within Francis Marion National Forest and designated as a wilderness area. The name appears on maps dating to at least 1757, and in 1761 James Colladon received a 500-acre grant on the swamp.

The name appears on a 1757 map of the South Carolina and Georgia coastline, and in 1761 James Colladon received a grant of 500 acres on the swamp. Two later stories, that Banastre Tarleton named it during the Revolutionary War or that bootleggers did during Prohibition, are both false: the 1773 James Cook map of South Carolina already locates Hell Hole Swamp.

The Hell Hole Swamp Festival is held on the first weekend of May at Jamestown, on the swamp's northern edge. Its events include a cocoa spitting contest, arm wrestling and beauty contests, plus the Hell Hole Gator Trot 10k, called the Redneck Run, begun in 1976 and one of South Carolina's oldest road races.

Hell Hole Swamp lies entirely inside Francis Marion National Forest in northeastern Berkeley County, with the festival town of Jamestown on its northern edge. The swamp has no marked trails or boardwalks, so plan on road access and forest roads rather than hiking paths. The Hell Hole Swamp Festival, held the first weekend of May in Jamestown, is the easiest time to see the area.

The swamp's name predates the Prohibition moonshine story: it already appears on a 1773 James Cook map of South Carolina, so the bootlegger explanation cannot be the origin. A group of Berkeley County natives, including Representative L. Mendel Rivers and Governor Robert Evander McNair, called themselves the Hell Hole Swamp Gang.