Museum of Science & Industry, Science museum in North Tampa, United States

The Museum of Science & Industry (MOSI) occupies a 190,000-square-foot science center on Fowler Avenue in North Tampa, completed in 1995 and linked by pedestrian bridge to the University of South Florida. Indoors are hands-on permanent exhibits, the Mission: Moonbase simulated lunar colony, and galleries for traveling shows; outside are a butterfly garden, science-themed mini-golf and a children's playground. Its Saunders Planetarium & Digital Dome Theatre, reopened in 2025, is the second-largest planetarium in the United States.

MOSI began in 1962, when Hillsborough County funded a youth museum in Sulphur Springs called the Museum of Science and Natural History. Renamed the Hillsborough County Museum in 1967, it moved to a new North Tampa building completed in 1980 and opened there on January 23, 1982. A 190,000-square-foot science center followed in 1995, and in January 2026 the museum took its current name, Museum of Science & Innovation.

MOSI has given the Hispanic Scientist of the Year Award since 2001, honoring Hispanic scientists who then meet children at Meet the Scientists Days and describe their paths into STEM fields. Its camps, held when school is out, cover topics such as snorkeling in a natural spring, DNA-based crime solving and video game design, and campers receive a S.T.E.A.M. Certificate of Achievement.

The location sits next to the University of South Florida campus, making it straightforward to find and reach. Most visitors spend several hours exploring the different exhibits, so plan accordingly.

Mission: Moonbase is set in 2070 in a simulated lunar base near the Moon's south pole, where frozen water is thought to lie in the rocks; NASA partly funds it. The Saunders Planetarium, opened in 1992, is the only planetarium in Tampa and, after a 2025 refit, the second-largest in the United States.